Rhododendron Research Network |
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Rhododendron Hybrid Pedigree Search Introduction Research Application Pedigrees are an excellent tool for designing experiments with hybrids. Comparing the phenotype of parents with that of offspring in the F1 and F2 generations can be the first step to determining which genes are responsible for a trait, and the genetic mechanisms of inheritance (e.g. transmission distortion, gene dominance and dosage effects). Genome-wide association studies, which involve scanning whole genomes for candidate genes, can also incorporate pedigrees to inform analysis, allowing a more targeted approach to increase the speed of discovery. Pedigrees themselves can also be used as data. For example, to build a recombination map, which reveals the relative influence of genetic linkages versus independent assortment, and has important consequences for inheritance. This information can also be used to discern the location and order of genes on the chromosomes. In addition, pedigrees can be used in combination with genotypic and phenotypic data to understand how populations change over time, and to reveal patterns and processes related to genetic diversity. For example, in determining how patterns of gene flow have contributed to population decline, or how deleterious alleles and small population sizes contribute to disease susceptibility. To Search Click Link ► Rhododendron Parentage Search |
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